Alzheimer’s Disease Metabolomics Consortium (ADMC)
The ADMC, led by Dr. Kaddurah-Daouk at Duke, unites top researchers to advance metabolomic profiling in large cohorts. Collaborating across AMP-AD, MODEL-AD, and MOVE-AD, the team integrates expertise in metabolomics, informatics, modeling, imaging, genetics, and clinical research.
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The Cardiovascular Health Study (CHS)Funded by NHLBI, CHS has tracked cardiovascular risk factors in adults 65+ since 1989. Participants underwent annual exams, including echocardiography, carotid ultrasound, and MRI, with follow-ups every six months. Key outcomes include CHD, stroke, heart failure, and mortality. With 2,000+ publications and 400+ ancillary studies, CHS continues to shape cardiovascular research.
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Danish Health RegistryManaged by the Danish Health Data Authority, this register supports hospital statistics, healthcare planning, disease tracking, and medical research. It includes data on hospital admissions since 1977, with ambulatory, emergency, and psychiatric cases added in 1995. Recorded variables cover personal details, admissions, diagnoses, treatments, and surgeries. Updated monthly, data access is available via the Danish Health Authority.
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Dog Aging ProjectAt the Dog Aging Project, we care deeply about the health and happiness of dogs. Our discoveries about healthy aging in our canine companions will translate into medical advances for people too. We’re working toward a future where dogs, and their humans, can live longer and stay healthier—together!
MoreELITE Portal
The ELITE Portal provides rich multi-omic datasets, computational tools, publications, and resources that empower researchers to discover novel therapeutic targets of health and disease. Learn more about our research domains and tools.
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Integrative Longevity Omics Project
This initiative integrates multi-omics data from centenarians, their offspring, and controls to identify protective profiles linked to exceptional longevity and Alzheimer's disease resistance. It also conducts tissue-specific analyses across 60 mammalian species to explore longevity factors. iPSCs from participants aged 103+ are differentiated into hepatocyte and CNS cell lines for functional studies of resilience.
MoreThe Health, Aging and Body Composition (HABC) Study
Health ABC examines risk factors for functional decline in older adults, focusing on body composition changes. While no longer recruiting, it remains a valuable resource for studying aging, disability, and disease. Researchers can submit proposals for data access.
MoreLong Life Family Study (LLFS)The LLFS studies families in the U.S. and Denmark with a strong history of exceptional longevity (EL). EL is a complex trait influenced by multiple genes and lifetime exposures. This research aims to uncover the genetic and environmental factors that contribute to healthy, long lives.
MoreMrOSThis prospective cohort study investigates how fracture risk in older men relates to bone mass, bone geometry, lifestyle, body measurements, neuromuscular function, and fall risk. It also examines the impact of fractures on quality of life.
MoreNew England Centenarian Study (NECS) The New England Centenarian Study (NECS) has studied centenarians and their families since 1995. Based at Boston University’s Chobanian and Avedisian School of Medicine since 2002, it is co-directed by Dr. Tom Perls and Dr. Stacy Andersen.
MoreThe Study of Osteoporotic Fractures (SOF)Funded by the NIH since 1986, SOF tracks osteoporosis and aging in women 65+, with 20 years of data. It covers fractures, breast cancer, mortality, bone density, hormones, strength, cognition, sleep, medication use, and more. Most data are available now.
MoreThe Study of Muscle Mobility and Aging (SOMMA)SOMMA tracks mobility loss in adults 70–90 using cutting-edge technology and rigorous methods to uncover new aging pathways.
MoreThe Vertebrate Genomes ProjectThe Vertebrate Genomes Project (VGP), a project of the G10K Consortium, aims to generate near error-free reference genome assemblies of ~70,000 extant vertebrate species. The VGP Species List details our Phase 1 Progress and includes a full list of the >70,000 extant, vertebrate species.
MoreCardiovascular Risk in Young Finns StudyThe Cardiovascular Risk in Young Finns Study is one of the largest long-term studies on cardiovascular risk from childhood to adulthood. It examines how childhood lifestyle, biological, and psychological factors influence adult cardiovascular risk. Its strengths include a longitudinal design with regular follow-ups, diverse phenotypes, and comprehensive lifestyle and socioeconomic data, allowing exploration of how early life factors contribute to common diseases.
MoreSTRIP StudyThe Special Turku Coronary Risk Factor Intervention Project (STRIP) is a one-of-a-kind study worldwide. It’s the only study that began dietary intervention in infancy, continued it for 20 years, and simultaneously collected data on a wide range of risk factors and subclinical cardiovascular markers.
MoreZoonomia ProjectThe Zoonomia Project is an international collaboration to discover the genomic basis of shared and specialized traits in mammals. We invite researchers across the scientific community to use our data, and to join us in harnessing the power of comparative genomics as a tool for human medicine and biodiversity conservation.
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